The checkered past of Capt. Jack Sparrow (Johnny Depp) catches up to him when he encounters Angelica (Penélope Cruz), a beautiful pirate that Jack once loved then left. Angelica forces him to accompany her to the Queen Anne’s Revenge, the ship of the notorious Blackbeard (Ian McShane). Accompanied by a zombie crew, the trio sets sail to find the legendary Fountain of Youth. However, Jack’s rival, Barbossa (Geoffrey Rush), also seeks the fountain, as does a ship from Spain.

Cast overview, first billed only:
	Johnny Depp	…	Jack Sparrow
	Penélope Cruz	…	Angelica
	Geoffrey Rush	…	Barbossa
	Ian McShane	…	Blackbeard
	Kevin McNally	…	Gibbs
	Sam Claflin	…	Philip
	Astrid Bergès-Frisbey	…	Syrena
	Stephen Graham	…	Scrum
	Keith Richards	…	Captain Teague
	Richard Griffiths	…	King George
	Jonny Rees	…	Groves (as Greg Ellis)
	Damian O’Hare	…	Gillette
	Óscar Jaenada	…	The Spaniard
	Anton Lesser	…	Lord John Carteret
	Roger Allam	…	Prime Minister Henry Pelham